8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Jul 4th 2026
ReturnsSun, Jul 12th 2026
Nights8
Departing PortMinneapolis/St. Paul
Ports of CallMinneapolis/St. Paul, Mississippi River, La Crosse, Cruising the River, Dubuque, Davenport, Hannibal, St Louis (2 Days)
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis… 
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Ocean View
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Balcony
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Suite
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Jul 11th 2026
ReturnsSun, Jul 19th 2026
Nights8
Departing PortSt Louis
Ports of CallSt Louis, Mississippi River, Hannibal, Cruising the River, Muscatine, Dubuque, Winona, Red Wing, Minneapolis/St. Paul
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…
Inside Cabin
Call for pricing
Ocean View
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Balcony
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Suite
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Jul 18th 2026
ReturnsSun, Jul 26th 2026
Nights8
Departing PortMinneapolis/St. Paul
Ports of CallMinneapolis/St. Paul, Mississippi River, La Crosse, Cruising the River, Dubuque, Davenport, Hannibal, St Louis (2 Days)
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…
Inside Cabin
Call for pricing
Ocean View
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Balcony
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Suite
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Jul 25th 2026
ReturnsSun, Aug 2nd 2026
Nights8
Departing PortSt Louis
Ports of CallSt Louis, Mississippi River, Hannibal, Cruising the River, Muscatine, Dubuque, Winona, Red Wing, Minneapolis/St. Paul
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…
Inside Cabin
Call for pricing
Ocean View
Call for pricing
Balcony
Call for pricing
Suite
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Prices are per person, double occupancy, cruise only and on select sailings. Prices shown are for stateroom categories as noted and are shown in US Dollars. Pricing listed includes taxes and fees. Airfare is not included. Prices and itineraries are based on availability and are subject to change without notice.
